BME110: Computational Biology Tools

Spring 2006
Tue/Thur 2-3:45pm
  Social Sciences 2 Rm 159

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Todd Lowe
Email: lowe @
Office: Physical Sciences Building, Rm 316
Phone: 459-1511
Office Hours:  Tues 11-Noon, Wed 4-5pm


Catalog Description:
Hands-on laboratory geared to teach basic tools used in computational biology (motif searching, primer selection, sequence comparison, multiple sequence alignment, genefinders, phylogenetics analysis, X-ray crystallography software). Web-based tools and databases are used. Open to all science students, with basic biochemistry or permission of the instructor as a  prerequsite.


You must bring your own laptop to class every day.
You will need a wireless network card to get on the network in class.
You will need to install the J2SE Java Runtime Environment (JRE) if haven't already (OS X users have Java built-in already)

Teaching Assistant:
Martina Koeva (martina
Hours: Mondays and Thursdays, 10:30-Noon, Physical Sciences Bldg, Rm 310

Required Text
Bioinformatics for Dummies
Jean-Michel Claverie & Cedric Notredame
Wiley Publishing, 2003
online resources

Additional Resources (Highly recommended)
Bioinformatics and Functional Genomics
Jonathan Pevsner
John Wiley & Sons, 2003

Problem Sets: 50%
Midterm: 20%
Final Exam: 30%

Course Topic Outline