October 22: Hands-On Exercise - Understanding ALDH2 Through its Structure

Accompanying Files:

• Exercise Questions: .doc | pdf

• PDB files:
  1O01_tetramer.pdb
  1O01_monomerB.pdb
  1ZUM.tetramer.pdb
  2ONM.tetramer.pdb

• Protein Sequence of ALDH2_HUMAN: P05091.fasta

• Culled (max. 70% sequence identity) List of ALDH2 Homologs
  Fasta List (139 sequences)
  MUSCLE alignment (.aln)

• MSA-based phylogenetic tree (Genebee-Treetop) of the culled70+target set, with bootstrap values (pdf)

• Web-Logo based on the same MSA (png)

• Non-obvious Links:
  Ultrabrief PyMol "tutorial"
  PISCES (Web Server + source download)
  MUSCLE (Web Server)
  Genebee TreeTop (Web Server)