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| Instructors: | |
| Carol Rohl rohl @ ucsc.edu 9-1729 Office Hours: Th 3-5pm 220 Sinsheimer |
Todd Lowe lowe @ soe.ucsc.edu 9-1511 Office Hours: T,F 2-3pm 227 Sinsheimer |
TA:
Corey Powell
cpowell @ soe.ucsc.edu
Office Hours: to be announced
Catalog Description:
Hands-on laboratory geared to teach basic tools used in computational biology
(motif searching, primer selection, sequence comparison, multiple sequence alignment,
genefinders, phylogenetics analysis, X-ray crystallography software). Web- and Unix-based
tools/databases are used. Open to all science students; no prior Unix experience required.
**IMPORTANT NOTE**
A goal in this course is for students to set up their own bioinformatics environment on the operating system with which they are most confortable. We highly encourage students to bring a laptop to class. If possible, we will conduct lab sessions and lectures concurrently, making use of the networking capabilities BE156. If you do not have access to a laptop computer that you can use for this class, please contact the instructors as soon as possible.
| Required Texts | |
|
Bioinformatics for Dummies Jean-Michel Claverie & Cedric Notredame Wiley Publishing, 2003 online resources |
Developing Bioinformatics Computer Skills Cynthia Gibas & Per Jambeck O'Reilley & Associates, 2001 |
| Additional Resources | |
| Introduction to Bioinformatics Arthur Lesk Wiley Publishing, 2003 |
Bioinformatics and Functional Genomics Jonathan Pevsner John Wiley & Sons, 2003 |
Grading:
Problem Sets: 80%
Final Exam: 20%
Course Outline: (syllabus)
Week 1: Using Bioinformatics Resources
Week 5: Multiple Sequence Alignment; Remote Homology Detection